Here are the key features:
Analgesic Properties: Co-codamol is a pain reliever that combines the effects of codeine, an opioid analgesic, and paracetamol (acetaminophen), a non-opioid analgesic, to provide effective pain relief.
Dosage: Each tablet typically contains 30mg of codeine phosphate and 500mg of paracetamol.
Pain Relief: It is used to relieve moderate to severe pain, such as post-operative pain, dental pain, musculoskeletal pain, and pain associated with menstrual cramps.
Dual Mechanism of Action: Codeine works by binding to opioid receptors in the brain and spinal cord, while paracetamol acts centrally and peripherally to reduce pain and fever.
Duration of Action: Co-codamol provides relief for several hours, typically around four to six hours per dose.
Side Effects: Common side effects may include dizziness, drowsiness, constipation, nausea, and vomiting. Long-term use can lead to dependence, tolerance, and addiction to codeine.
Avoidance of Alcohol: Consumption of alcohol while taking co-codamol can increase the risk of adverse effects such as respiratory depression and liver damage.
Liver Function Monitoring: Since paracetamol is metabolized in the liver, it’s important to monitor liver function, especially with prolonged or high-dose use, to avoid hepatotoxicity.
Interaction with Other Medications: Co-codamol should be used cautiously with other medications that depress the central nervous system, such as benzodiazepines, as it can potentiate their effects.
Always follow the guidance of a healthcare professional regarding the appropriate use, dosage, and potential side effects of co-codamol tablets, as individual circumstances may vary.